Short Communication

Evaluation of The Efficacy of Long-Term Growth Hormone Therapy in Patients with Hypochondroplasıa


  • Tuğba Çetin
  • Zeynep Şıklar
  • Pınar Kocaay
  • Merih Berberoğlu

J Clin Res Pediatr Endocrinol 0;0(0):0-0 [e-Pub] PMID: 29739731

Hypochondroplasia is a cause of disproportionate short stature and characterized by slight clinical manifestations. The aim of this study was to evaluate the efficacy of long-term GH therapy in hypochondroplastic cases with inadequate response to GH simulation tests . In this study, six patients who had height SDS of -3.43 before the treatment and a mean age of 7.42 and received GH treatment at a dose of 0.2 mg / kg / week for a mean of 4.45 years were evaluated. As a result, a good accepted response was found in the first year in hypochondroplastic patients with findings of GH deficiency, but this increase was not found to be sufficient in the patients who achieved the final height.

Keywords: hypochondroplasia, growth hormone therapy, skeletal dysplasia