Neonatal Hypopituitarism: Diagnosis and Treatment Approaches


  • Selim Kurtoğlu
  • Ahmet Özdemir
  • Nihal Hatipoğlu

Received Date: 01.02.2018 Accepted Date: 08.05.2018 J Clin Res Pediatr Endocrinol 0;0(0):0-0 [e-Pub] PMID: 29739730

Hypopituitarism is defined as a decreased release of hypophysis hormones, which may be caused by pituitary gland disease or hypothalamus disease. Clinical findings for neonatal hypopituitarism depend on causes and hormonal deficiency type and degree. Patients may be asymptomatic or may demonstrate non-specific symptoms, but may still be under risk for development of hypophysis hormone deficiency with time. Anamnesis, physical examination, endocrinological, radiological and genetic evaluations are all important for early diagnosis and treatment. Treatment of hypopituitarism patients is possible through treatment of hypophysis and hypothalamus disorders. The aim of this article is to contribute to the literature through a review of etiological factors, clinical findings, diagnoses and treatment approaches for neonatal hypopituitarism.

Keywords: Diagnosis, hypophysis, hypothalamus, neonatal hypopituitarism, treatment