A 15-year-old Girl with a Lateral Neck Mass Turning Out to Be Papillary Thyroid Carcinoma - Lateral Ectopic Papillary Thyroid Carcinoma or Lymph Node Metastasis?
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Case Report

A 15-year-old Girl with a Lateral Neck Mass Turning Out to Be Papillary Thyroid Carcinoma - Lateral Ectopic Papillary Thyroid Carcinoma or Lymph Node Metastasis?

J Clin Res Pediatr Endocrinol 2025;17(2):231-236 DOI: 10.4274/jcrpe.galenos.2023.2023-4-6
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Abstract

Lateral neck lesions in children are common and involve various infectious or inflammatory etiologies, as well as embryological remnants such as branchial cleft cysts. Although unusual, ectopic thyroid tissue may also present as a lateral neck mass. Here, we present an unusual case of a 15-year-old girl treated for an asymptomatic lateral neck mass that, after surgical removal, was found to be papillary thyroid carcinoma (PTC). However, after removal of the thyroid gland, no primary thyroid tumor was found. The question arose whether the lateral neck lesion was a lymph node metastasis without identifiable primary tumor by histological evaluation, or rather malignant degeneration of ectopic thyroid tissue. Total thyroidectomy was performed with postoperative adjuvant radioactive iodine ablation. Even though PTC in a lateral neck mass without a primary thyroid tumor has been described previously, pediatric cases have not been reported. In this report we share our experience on diagnosis, treatment and follow-up, and review the existing literature.

Keywords: Thyroid dysgenesis, thyroid papillary carcinoma, cervical neck mass

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