J Clin Res Pediatr Endocrinol. 2023; 15(1): 103-107 | DOI: 10.4274/jcrpe.galenos.2021.2021.0121

Maltodextrin May Be a Promising Treatment Modality After Near-total Pancreatectomy in Infants Younger Than Six Months with Persistent Hyperinsulinism: A Case Report

Yasemin Denkboy Öngen, Erdal Eren, Halil Saðlam
Bursa Uludað University Faculty of Medicine, Department of Pediatric Endocrinology, Bursa, Turkey

Persistent hypoglycemia in infants with congenital hyperinsulinism (CHI) can be challenging in approximately half of these cases, even after undergoing a near-total pancreatectomy. While maltodextrin has been recommended in the nutritional management of CHI cases younger than six months, information regarding its efficacy in managing hypoglycemia are not yet clear. Here, we present a male infant with CHI who experienced persistent hypoglycemia even after undergoing a near-total pancreatectomy and despite multiple medical treatments. The infant’s hypoglycemic episodes were successfully controlled by adding maltodextrin to his diet.

Keywords: Congenital hyperinsulinism, ABCC8 gene, maltodextrin, near-total pancreatectomy, continue glucose monitoring systems

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