Metabolic Syndrome Features Presenting in Early Childhood in Alström Syndrome: A Case Report
Özgür Pirgon1, Mehmet Emre Atabek2, İlhan Asya Tanju31Department Of Pediatric Endocrinology, Konya Research Hospital, Konya, Turkey 2Department Of Pediatric Endocrinology, Medical Faculty, Selçuk University, Konya, Turkey 3Department Of Pediatrics, Gata Medical Faculty, İstanbul, Turkey
Alström syndrome is a rare autosomal recessive disorder characterized by retinal degeneration, sensorineural hearing loss, early-onset obesity, and non-insulin-dependent diabetes mellitus. Affected individuals have normal birth weight, but growth deceleration starts at about 8-10 years of age. In patients with the disorder linked to chromosome 2, the increase in body mass index is very high in childhood and continues high thereafter. In this paper, we report a patient who had the proposed diagnostic criteria for Alström syndrome associated with metabolic syndrome starting at age 7, a relatively early age.
Özgür Pirgon, Mehmet Emre Atabek, İlhan Asya Tanju. Metabolic Syndrome Features Presenting in Early Childhood in Alström Syndrome: A Case Report. J Clin Res Pediatr Endocrinol. 2009; 1(6): 278-280 Manuscript Language: English