J Clin Res Pediatr Endocrinol. 2012; 4(1): 30-33 | DOI: 10.4274/jcrpe.477
Synchronous Occurrence of Papillary Carcinoma in the Thyroid Gland and Thyroglossal Duct in an Adolescent with Congenital Hypothyroidism
Zeynep Şıklar1, Merih Berberoğlu1, Aydın Yağmurlu2, Bülent Hacıhamdioğlu1, Şenay Savaş Erdeve1, Suat Fitöz3, Metin Kır4, Gönül Öçal11Ankara University Faculty Of Medicine, Department Of Pediatrics Endocrinology, Ankara, Turkey
2Ankara University Faculty Of Medicine, Department Of Pediatric Surgery, Ankara, Turkey
3Ankara University Faculty Of Medicine, Department Of Pediatric Radiology, Ankara, Turkey
4Ankara University Faculty Of Medicine, Department Of Nuclear Medicine, Ankara, Turkey
Thyroid carcinoma (TC) combined with congenital hypothyroidism is rare. The synchronous occurrence of these two conditions is even rarer. We describe a patient with congenital hypothyroidism in whom hyperthyroglobulinemia and nodules developed despite adequate replacement therapy. Papillary TC was detected at age 19 years. Postoperative diagnostic scintigraphy showed increased uptake in the thyroglossal duct region. Repetitive imaging of the thyroid gland can be useful in the early detection of TC in patients with congenital hypothyroidism. Moreover, this rare situation can be complicated by a synchronous thyroglossal duct carcinoma. Thyroglossal duct carcinoma can be detected if diagnostic scintigraphy is performed after total thyroidectomy.
Keywords: Congenital,hypothyroidism,differentiated thyroid carcinoma,synchronous,thyroglossal duct carcinoma
Zeynep Şıklar, Merih Berberoğlu, Aydın Yağmurlu, Bülent Hacıhamdioğlu, Şenay Savaş Erdeve, Suat Fitöz, Metin Kır, Gönül Öçal. Synchronous Occurrence of Papillary Carcinoma in the Thyroid Gland and Thyroglossal Duct in an Adolescent with Congenital Hypothyroidism. J Clin Res Pediatr Endocrinol. 2012; 4(1): 30-33
Manuscript Language: English