J Clin Res Pediatr Endocrinol. 2013; 5(1): 50-54 | DOI: 10.4274/Jcrpe.778

Reevaluation of the Prevalence of Metabolic ?Syndrome in an Urban Area of Turkey

Mehmet Emre Atabek¹, Beray Selver Eklioðlu¹, Nesibe Akyürek¹
Necmettin Erbakan University, School of Medicine, Department of Pediatric Endocrinology, Konya, Turkey

Objective: Our aim was to reveal a change in the prevalence of metabolic syndrome (MS) in the province of Konya in five years.
Methods: We studied 202 obese children and adolescents (body mass index >95th percentile) aged between 7 and 18 years. The diagnosis of impaired glucose tolerance, type 2 diabetes mellitus (T2DM), and MS were defined according to the modified World Health Organization criteria adapted for children.
Results: MS was found in 56.4 % with a significantly higher rate among adolescents aged 12-18 years (63.2%) than among prepubertal children aged 7-11 years (47%) (p=0.01). The prevalence figures for insulin resistance, glucose intolerance, and T2DM were 60, 8, and 2% among prepubertal children and 81.8, 12.8, and 0% among adolescents, respectively. The prevalence of fasting hyperinsulinemia in adolescents was significantly higher than in prepubertal children (p<0.001). Hypertension was significantly more common in adolescents (42.8%) than in prepubertal children (32.9%) (p=0.04).
Conclusions: We found that the incidence of MS in the city center of Konya approximately doubled in the last five years with increased rates of morbidity and abnormal lipid profiles.

Keywords: Childhood obesity, metabolic syndrome, insulin resistance, impaired glucose tolerance, type 2 diabetes

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