Iodine Overload and Severe Hypothyroidism in Two Neonates
Selim Kurtoğlu1, Leyla Akın2, Mustafa Ali Akın3, Dilek Çoban31Erciyes University, Faculty Of Medicine, Department Of Pediatric Endocrinology, Kayseri, Turkey 2Erciyes University Faculty of Medicine, Department of Pediatric Endocrinology, Kayseri, Turkey 3Erciyes University, Faculty Of Medicine, Department Of Neonatology, Kayseri, Turkey
Iodine overload frequently leads to transient hyperthyrotropinemia or hypothyroidism, and rarely to hyperthyroidism in neonates. Iodine exposure can be prenatal, perinatal or postnatal. Herein we report two newborn infants who developed severe hypothyroidism due to iodine overload. The overloading was caused by excessive use of an iodinated antiseptic for umbilical care in the first case, and as a result of maternal exposure and through breast milk with a high iodine level in the second case. Presenting the two cases, we wanted to draw attention to these preventable causes of hypothyroidism in infants.
Keywords: Neonate,hypothyroidism,Iodine overload
Selim Kurtoğlu, Leyla Akın, Mustafa Ali Akın, Dilek Çoban. Iodine Overload and Severe Hypothyroidism in Two Neonates. J Clin Res Pediatr Endocrinol. 2009; 1(6): 275-277 Manuscript Language: English