ISSN: 1308-5727 | E-ISSN: 1308-5735
Volume : Issue : Year : 2022
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Abstracting & Indexing
Turkish Society for Pediatric Endocrinology and Diabetes
Incidence of Newly Diagnosed Type 1 Diabetes Mellitus in Children and Adolescents in Henan Province of China from 2017 to 2020: A Retrospective Multicenter Study Based on Hospitalization Data [J Clin Res Pediatr Endocrinol]
J Clin Res Pediatr Endocrinol. Ahead of Print: JCRPE-17363 | DOI: 10.4274/jcrpe.galenos.2022.2021-12-4

Incidence of Newly Diagnosed Type 1 Diabetes Mellitus in Children and Adolescents in Henan Province of China from 2017 to 2020: A Retrospective Multicenter Study Based on Hospitalization Data

Qiong Chen1, Na Xu2, Yongxing Chen1, Mingming Yan3, Fengyan Tian4, Wei Yang1, Yan Cui1, Ai Huang1, Yangshiyu Li1, He Zhang5, Zhihong Jiang6, Ruizhi Zheng7, Yuan Ji8, Dongming Zhang9, Qiao Ren10, Li Ding11, Haiyan Wei1
1Department of Endocrinology, Genetics and Metabolism, Children’s Hospital Affiliated to Zhengzhou University, Henan Children’s Hospital, Zhengzhou Children’s Hospital, Henan, China
2Department of Endocrinology, Nanyang Central Hospital,Henan,China
3Henan Key Laboratory of Children’s Genetics and Metabolic Diseases, Children’s Hospital Affiliated to Zhengzhou University, Henan Children’s Hospital, Zhengzhou Children’s Hospital, Henan, China
4Department of Pediatrics, The First Affiliated Hospital of Zhengzhou University, Henan, China
5Department of Endocrinology, The First Affiliated Hospital of Xinxiang Medical University, Henan, China
6Department of Endocrinology, The First Affiliated Hospital of Henan University of Science and Technology, Henan, China
7Department of Endocrinology, Henan Provincial People’s Hospital, Henan, China
8Department of Endocrinology, Kaifeng Children’s Hospital, Henan, China
9Department of Endocrinology, The Second Affiliated Hospital of Zhengzhou University, Henan, China
10Department of Endocrinology, 989 Hospital of PLA Joint Logistics Support Force, Henan, China
11Department of Pediatrics, Anyang Maternal and Childcare Hospital, China

INTRODUCTION: Background: The incidence of type 1 diabetes mellitus (T1DM) is rapidly increasing worldwide. However, the incidence in Henan Province of China has been unknown for more than two decades. This study aimed to estimate the incidence of T1DM in the 0.5-14.9 years age group in Henan Province of China from 2017 to 2020.
METHODS: Methods: A retrospective analysis of hospital registration data from 18 cities in Henan Province, China, identified 1726 patients (843 males, 883 females) between 0.5-14.9 years of age with newly diagnosed T1DM in Henan Province from January 1st, 2017, to December 31st, 2020, covering more than 19 million children years at risk.
RESULTS: Results: The crude incidence of T1DM per 100 000 person years for the 0.5-14.9 years age group in the Henan Province of China was 2.19 (95% confidence interval (CI): 1.99, 2.40), with a peak in the 10-14.9 years age group. The rate ratio of females to males was 1.32 (95% CI: 1.20, 1.45) in the 0.5-14.9 years age group. The incidence rate was higher in females than males in the 5-9.9 years age group (P˂0.01) and the 10-14.9 years age group (P˂0.01). The seasonality of the incidence was different from that in previous reports, with the lowest incidence in the spring.
DISCUSSION AND CONCLUSION: Conclusion: The incidence of T1DM in the 0.5-14.9 years age group in Henan Province of China was still among the lowest reported according to our study.

Keywords: incidence, type 1 diabetes mellitus; children; China; new onset



Corresponding Author: Haiyan Wei, China
Manuscript Language: English
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