ISSN: 1308-5727 | E-ISSN: 1308-5735
Volume : 3 Issue : 4 Year : 2024
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Turkish Society for Pediatric Endocrinology and Diabetes
Resolution of Autoimmune Oophoritis after Thymectomy in a Myasthenia Gravis Patient [J Clin Res Pediatr Endocrinol]
J Clin Res Pediatr Endocrinol. 2011; 3(4): 212-215 | DOI: 10.4274/jcrpe.378

Resolution of Autoimmune Oophoritis after Thymectomy in a Myasthenia Gravis Patient

Esra Deniz Papatya Çakır1, Özlem Özdemir2, Erdal Eren1, Halil Sağlam1, Mehmet Okan2, Ömer Faruk Tarım1
1Uludağ University School Of Medicine, Pediatric Endocrinology, Bursa, Turkey
2Uludağ University School Of Medicine, Pediatric Neurology, Bursa, Turkey

Myasthenia gravis (MG) is an autoimmune disorder characterized by autoantibodies against acetylcholine receptors. MG is generally an isolated disorder but may occur concomitantly with other autoimmune diseases. We describe an eighteen-year-old girl with MG who was admitted to our clinic with secondary amenorrhea and diagnosed as autoimmune oophoritis. Since her myasthenic symptoms did not resolve with anticholinesterase therapy, thymectomy was performed. After thymectomy, her menses have been regular without any hormonal replacement therapy. To our knowledge, this is the first report on a patient with autoimmune ovarian insufficiency and MG in whom premature ovarian insufficiency resolved after thymectomy, without hormonal therapy.

Keywords: Autoimmune oophoritis,myasthenia gravis,thymectomy

Esra Deniz Papatya Çakır, Özlem Özdemir, Erdal Eren, Halil Sağlam, Mehmet Okan, Ömer Faruk Tarım. Resolution of Autoimmune Oophoritis after Thymectomy in a Myasthenia Gravis Patient. J Clin Res Pediatr Endocrinol. 2011; 3(4): 212-215
Manuscript Language: English
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