ISSN: 1308-5727 | E-ISSN: 1308-5735
Volume : 1 Issue : 6 Year : 2024
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Turkish Society for Pediatric Endocrinology and Diabetes
Vitamin D Deficiency in Turkish Mothers and Their Neonates and in Women of Reproductive Age [J Clin Res Pediatr Endocrinol]
J Clin Res Pediatr Endocrinol. 2009; 1(6): 266-269 | DOI: 10.4274/jcrpe.v1i6.266

Vitamin D Deficiency in Turkish Mothers and Their Neonates and in Women of Reproductive Age

Ayça Törel Ergür1, Merih Berberoğlu1, Begüm Atasay2, Zeynep Şıklar1, Pelin Bilir1, Saadet Arsan2, Feride Söylemez3, Gönül Öcal1
1Ankara University, School Of Medicine, Departments Of Pediatric Endocrinology, Ankara, Turkey
2Ankara University, School Of Medicine, Departments Of Neonatology, Ankara, Turkey
3Ankara University, School Of Medicine, Departments Of Gynecology And Obstetrics, Ankara, Turkey

Objective: Materno-fetal vitamin D deficiency (VDD) may occur in the early neonatal period. We aimed to evaluate the vitamin D (vitD) status and risk factors for VDD in healthy newborns and their mothers, and also in fertile women.
Methods: Serum 25 hydroxyvitamin D3 (25(OH)D), calcium (Ca), phosphorus (P) and alkaline phosphatase (ALP) levels were measured in 70 mothers (study group) and their newborns, and in umbilical cord samples. 104 nonpregnant fertile women comprised the control group. Demographic factors such as education and clothing habits of the mother, number of pregnancies and month of delivery were recorded. A serum 25(OH)D level below 11 ng/ml was accepted as severe, 11-25 ng/ml as moderate VDD, and a value over 25ng/ml as normal.
Results: Severe VDD was found in 27% of the mothers, and moderate deficiency in 54.3%. Severe VDD was detected in 64.3% of the neonates, and moderate deficiency in 32.9%. Only 18.6% of the mothers and 2.9 % of the neonates had normal vitD levels. In thecontrol group, severe VDD was observed in 26.9%, and moderatedeficiency in 45.2 %. Only 27.8 % of the controls had normal vitD levels. In the control group, the 25(OH)D levels of the women dressed in modern clothes were significantly higher than those of the women wearing traditional clothes. This difference was not observed in the study group because 75% of these 70 mothers wore modern clothes. Mothers giving birth during the summer months and their neonates had significantly higher serum 25(OH)D levels than those of the mothers giving birth during the winter months and their neonates.
Conclusion: The study has shown that in Turkey VDD is an important problem in women of reproductive age, in mothers and their neonates. The 25(OH)D levels obtained from the cord may serve as a guide in the determination of the high risk groups.

Keywords: 25OHD,newborn,mother,cord,reproductive age women

Ayça Törel Ergür, Merih Berberoğlu, Begüm Atasay, Zeynep Şıklar, Pelin Bilir, Saadet Arsan, Feride Söylemez, Gönül Öcal. Vitamin D Deficiency in Turkish Mothers and Their Neonates and in Women of Reproductive Age. J Clin Res Pediatr Endocrinol. 2009; 1(6): 266-269
Manuscript Language: English
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