ISSN: 1308-5727 | E-ISSN: 1308-5735
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Turkish Society for Pediatric Endocrinology and Diabetes
Metabolic Bone Disease of Prematurity: Report of Four Cases [J Clin Res Pediatr Endocrinol]
J Clin Res Pediatr Endocrinol. 2014; 6(2): 111-115 | DOI: 10.4274/jcrpe.1282

Metabolic Bone Disease of Prematurity: Report of Four Cases

Gül Yeşiltepe Mutlu1, Heves Kırmızıbekmez1, Elif Özsu2, İlkay Er3, Şükrü Hatun2
1Zeynep Kamil Gynecologic And Pediatric Training And Research Hospital, Department Of Pediatric Endocrinology, İstanbul, Turkey
2Kocaeli University Faculty Of Medicine, Department Of Pediatric Endocrinology And Diabetes, Kocaeli, Turkey
3Kocaeli University Faculty Of Medicine, Department Of Neonatology, Kocaeli, Turkey

Osteopenia of prematurity has become a common problem recently because of improved survival rates of infants with very low birth weight (VLBW). The incidence of neonatal osteopenia is inversely correlated with gestational age and birth weight. Herein, we present four cases of preterm osteopenia that were referred to the pediatric endocrinology outpatient clinic with diverse clinical and laboratory findings and we discuss the clinical course of these infants with regard to bone disease after discharge from the neonatal intensive care unit (NICU). This report highlights the importance of enteral calcium, phosphorus and vitamin D support at adequate doses following discharge from NICU for preterm infants with VLBW who are at risk of metabolic bone disease.

Keywords: Metabolic Bone Disease,prematurity,phosphorus,Alkaline phosphatase,Vitamin D

Gül Yeşiltepe Mutlu, Heves Kırmızıbekmez, Elif Özsu, İlkay Er, Şükrü Hatun. Metabolic Bone Disease of Prematurity: Report of Four Cases. J Clin Res Pediatr Endocrinol. 2014; 6(2): 111-115
Manuscript Language: English
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