Growth curves for Turkish Girls with Turner Syndrome: Results of the Turkish Turner Syndrome Study Group

Darendeliler, Feyza; Ye�ilkaya, Ediz; Bereket, Abdullah; Ba�, Firdevs; Bundak, R�veyde; Sar�, Erkan; K���kemre Ayd�n, Banu; Darcan, ��kran; D�ndar, Bumin; B�y�kinan, Muammer; Kara, Cengiz; Maz�c�o�lu, M�mtaz M.; Adal, Erdal; Ak�nc�, Ay�ehan; Atabek, Mehmet Emre; Demirel, Fatma; �elik, Nurullah; �zkan, Behzat; �zhan, Bayram; Orbak, Zerrin; Ersoy, Bet�l; Do�an, Murat; Ata�, Ali; Turan, Serap; G�k�en, Damla; Tar�m, �mer; Y�ksel, Bilgin; Ercan, Oya; Hatun, ��kr�; �im�ek, Enver; �kten, Ay�enur; Abac�, Ayhan; D�neray, Hakan; �zbek, Mehmet Nuri; Keskin, Mehmet; �nal, Hasan; Aky�rek, Nesibe; Bulan, Kezban; Tepe, Derya; Emeksiz, Hamdi Cihan; Demir, Korcan; K�z�lay, Deniz; Topalo�lu, Ali Kemal; Eren, Erdal; �zen, Samim; Demirbilek, H�seyin; Abal�, Sayg�n; Ak�n, Leyla; Selver Eklio�lu, Beray; Kaba, Sultan; An�k, Ahmet; Ba�, Serpil; �n�var, Tolga; Sa�lam, Halil; Bolu, Semih; �zgen, Tolga; Do�an, Durmu�; �ak�r, Esra Deniz; �en, Ya�ar; And�ran, Nesibe; �izmecio�lu, Filiz; Evliyao�lu, Olcay; Karag�zel, G�lay; Pirgon, �zg�r; �atl�, G�n�l; Can, Hatice Dilek; G�rb�z, Fatih; Binay, �i�dem; Ba�, Veysel Nijat; Sa�lam, Celal; G�l, Davut; Polat, Adem; A��kel, Cengizhan; Cinaz, Peyami

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Turkish Society for Pediatric Endocrinology and Diabetes

Growth curves for Turkish Girls with Turner Syndrome: Results of the Turkish Turner Syndrome Study Group [J Clin Res Pediatr Endocrinol]

J Clin Res Pediatr Endocrinol. 2015; 7(3): 183-191 | DOI: 10.4274/jcrpe.2023

Growth curves for Turkish Girls with Turner Syndrome: Results of the Turkish Turner Syndrome Study Group

Feyza Darendeliler¹, Ediz Ye�ilkaya², Abdullah Bereket³, Firdevs Ba�¹, R�veyde Bundak¹, Erkan Sar�², Banu K��kemre Ayd�n¹, ��kran Darcan⁴, Bumin D�ndar⁵, Muammer B�y�kinan⁶, Cengiz Kara⁷, M�mtaz M. Maz�c�o�lu⁸, Erdal Adal⁹, Ay�ehan Ak�nc�¹⁰, Mehmet Emre Atabek¹¹, Fatma Demirel¹², Nurullah �elik¹³, Behzat �zkan¹⁴, Bayram �zhan¹⁵, Zerrin Orbak¹⁶, Bet�l Ersoy¹⁷, Murat Do�an¹⁸, Ali Ata�¹⁹, Serap Turan³, Damla G�k�en⁴, �mer Tar�m²⁰, Bilgin Y�ksel²¹, Oya Ercan²², ��kr� Hatun²³, Enver �im�ek²⁴, Ay�enur �kten²⁵, Ayhan Abac�²⁶, Hakan D�neray¹⁶, Mehmet Nuri �zbek²⁷, Mehmet Keskin²⁸, Hasan �nal⁹, Nesibe Aky�rek¹¹, Kezban Bulan¹¹, Derya Tepe¹², Hamdi Cihan Emeksiz¹³, Korcan Demir¹⁴, Deniz K�z�lay¹⁷, Ali Kemal Topalo�lu²¹, Erdal Eren²⁰, Samim �zen⁴, H�seyin Demirbilek²⁷, Sayg�n Abal�³, Leyla Ak�n²⁹, Beray Selver Eklio�lu¹¹, Sultan Kaba¹⁸, Ahmet An�k³⁰, Serpil Ba�³, Tolga �n�var⁹, Halil Sa�lam²⁰, Semih Bolu³¹, Tolga �zgen⁹, Durmu� Do�an²⁰, Esra Deniz �ak�r²⁰, Ya�ar �en³², Nesibe And�ran¹², Filiz �izmecio�lu²³, Olcay Evliyao�lu²², G�lay Karag�zel²⁵, �zg�r Pirgon³³, G�n�l �atl�³⁰, Hatice Dilek Can²⁰, Fatih G�rb�z²¹, �i�dem Binay²⁴, Veysel Nijat Ba�³⁴, Celal Sa�lam², Davut G�l², Adem Polat², Cengizhan A��kel², Peyami Cinaz¹³
¹�stanbul University Istanbul Faculty Of Medicine, Department Of Pediatric Endocrinology, �stanbul, Turkey
²G�lhane Military Medicine Academy, Department Of Pediatric Endocrinology, Ankara, Turkey
³Marmara University Faculty Of Medicine, Department Of Pediatric Endocrinology, �stanbul, Turkey
⁴Ege University Faculty Of Medicine, Department Of Pediatric Endocrinology, �zmir, Turkey
⁵Katip �elebi University Faculty Of Medicine, Department Of Pediatric Endocrinology, �zmir, Turkey
⁶Konya Training And Research Hospital, Clinic Of Pediatric Endocrinology, Konya, Turkey
⁷On Dokuz May�s University Faculty Of Medicine, Department Of Pediatric Endocrinology, Samsun, Turkey
⁸Erciyes University Faculty Of Medicine, Department Of Pediatric Endocrinology, Kayseri, Turkey
⁹Kanuni Sultan S�leyman Training And Research Hospital, Clinic Of Pediatric Endocrinology, �stanbul, Turkey
¹⁰In�n� University Faculty Of Medicine, Department Of Pediatric Endocrinology, Malatya, Turkey
¹¹Necmettin Erbakan University Faculty Of Medicine, Department Of Pediatric Endocrinology, Konya, Turkey
¹²Y�ld�r�m Beyaz�t University Faculty Of Medicine, Department Of Pediatric Endocrinology, Ankara, Turkey
¹³Gazi University Faculty Of Medicine, Department Of Pediatric Endocrinology, Ankara, Turkey
¹⁴Dr. Beh�et Uz Children Hospital, Clinic Of Pediatric Endocrinology, �zmir, Turkey
¹⁵Pamukkale University Faculty Of Medicine, Department Of Pediatric Endocrinology, Denizli, Turkey
¹⁶Atat�rk University Faculty Of Medicine, Department Of Pediatric Endocrinology, Erzurum, Turkey
¹⁷Celal Bayar University Faculty Of Medicine, Department Of Pediatric Endocrinology, Manisa, Turkey
¹⁸Y�z�nc� Y�l University Faculty Of Medicine, Department Of Pediatric Endocrinology, Van, Turkey
¹⁹Harran University Faculty Of Medicine, Department Of Pediatric Endocrinology, �anl�urfa, Turkey
²⁰Uluda� University Faculty Of Medicine, Department Of Pediatric Endocrinology, Bursa, Turkey
²¹�ukurova University Faculty Of Medicine, Department Of Pediatric Endocrinology, Adana, Turkey
²²�stanbul University Cerrahpa�a Faculty Of Medicine, Department Of Pediatric Endocrinology, �stanbul, Turkey
²³Kocaeli University Faculty Of Medicine, Department Of Pediatric Endocrinology, Kocaeli, Turkey
²⁴Osmangazi University Faculty Of Medicine, Department Of Pediatric Endocrinology, Eski�ehir, Turkey
²⁵Karadeniz Technical University Faculty Of Medicine, Department Of Pediatric Endocrinology, Trabzon, Turkey
²⁶Dokuz Eyl�l University Faculty of Medicine, Department of Pediatric Endocrinology, �zmir, Turkey
²⁷Diyarbak�r Training And Research Hospital, Clinic Of Pediatric Endocrinology, Diyarbak�r, Turkey
²⁸Gaziantep University Faculty Of Medicine, Department Of Pediatric Endocrinology, Gaziantep, Turkey
²⁹Erciyes University Faculty of Medicine, Department of Pediatric Endocrinology, Kayseri, Turkey
³⁰Dokuz Eyl�l University Faculty Of Medicine, Department Of Pediatric Endocrinology, �zmir, Turkey
³¹D�zce University Faculty Of Medicine, Department Of Pediatric Endocrinology, D�zce, Turkey
³²Sel�uk University Faculty Of Medicine, Department Of Pediatric Endocrinology, Konya, Turkey
³³S�leyman Demirel University Faculty Of Medicine, Department Of Pediatric Endocrinology, Isparta, Turkey
³⁴Kayseri Training And Research Hospital, Clinic Of Pediatric Endocrinology, Kayseri, Turkey

Objective: Children with Turner syndrome (TS) have a specific growth pattern that is quite different from that of healthy children. Many countries have population-specific growth charts for TS. Considering national and ethnic differences, we undertook this multicenter collaborative study to construct growth charts and reference values for height, weight and body mass index (BMI) from 3 years of age to adulthood for spontaneous growth of Turkish girls with TS.
Methods: Cross-sectional height and weight data of 842 patients with TS, younger than 18 years of age and before starting any therapy, were evaluated.
Results: The data were processed to calculate the 3rd, 10th, 25th, 50th, 75th, 90th and 97th percentile values for defined ages and to construct growth curves for height-for-age, weight-for-age and BMI-for-age of girls with TS. The growth pattern of TS girls in this series resembled the growth pattern of TS girls in other reports, but there were differences in height between our series and the others.
Conclusion: This study provides disease-specific growth charts for Turkish girls with TS. These disease-specific national growth charts will serve to improve the evaluation of growth and its management with growth-promoting therapeutic agents in TS patients.

Keywords: Turner syndrome,growth charts,body mass index charts,Turkish children

Feyza Darendeliler, Ediz Ye�ilkaya, Abdullah Bereket, Firdevs Ba�, R�veyde Bundak, Erkan Sar�, Banu K��kemre Ayd�n, ��kran Darcan, Bumin D�ndar, Muammer B�y�kinan, Cengiz Kara, M�mtaz M. Maz�c�o�lu, Erdal Adal, Ay�ehan Ak�nc�, Mehmet Emre Atabek, Fatma Demirel, Nurullah �elik, Behzat �zkan, Bayram �zhan, Zerrin Orbak, Bet�l Ersoy, Murat Do�an, Ali Ata�, Serap Turan, Damla G�k�en, �mer Tar�m, Bilgin Y�ksel, Oya Ercan, ��kr� Hatun, Enver �im�ek, Ay�enur �kten, Ayhan Abac�, Hakan D�neray, Mehmet Nuri �zbek, Mehmet Keskin, Hasan �nal, Nesibe Aky�rek, Kezban Bulan, Derya Tepe, Hamdi Cihan Emeksiz, Korcan Demir, Deniz K�z�lay, Ali Kemal Topalo�lu, Erdal Eren, Samim �zen, H�seyin Demirbilek, Sayg�n Abal�, Leyla Ak�n, Beray Selver Eklio�lu, Sultan Kaba, Ahmet An�k, Serpil Ba�, Tolga �n�var, Halil Sa�lam, Semih Bolu, Tolga �zgen, Durmu� Do�an, Esra Deniz �ak�r, Ya�ar �en, Nesibe And�ran, Filiz �izmecio�lu, Olcay Evliyao�lu, G�lay Karag�zel, �zg�r Pirgon, G�n�l �atl�, Hatice Dilek Can, Fatih G�rb�z, �i�dem Binay, Veysel Nijat Ba�, Celal Sa�lam, Davut G�l, Adem Polat, Cengizhan A��kel, Peyami Cinaz. Growth curves for Turkish Girls with Turner Syndrome: Results of the Turkish Turner Syndrome Study Group. J Clin Res Pediatr Endocrinol. 2015; 7(3): 183-191
Manuscript Language: English

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