ISSN: 1308-5727 | E-ISSN: 1308-5735
Volume : 14 Issue : 4 Year : 2022
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Abstracting & Indexing
Turkish Society for Pediatric Endocrinology and Diabetes
Advances in Diagnosis and Management of Childhood Osteoporosis [J Clin Res Pediatr Endocrinol]
J Clin Res Pediatr Endocrinol. 2022; 14(4): 370-384 | DOI: 10.4274/jcrpe.galenos.2022.2022-8-3

Advances in Diagnosis and Management of Childhood Osteoporosis

David B.N. Lim1, Rebecca J. Moon2, Justin H. Davies3
1University Hospital Southampton NHS Foundation Trust, Southampton Children’s Hospital, Paediatric Endocrinology, Hampshire, England
2University Hospital Southampton NHS Foundation Trust, Southampton Children’s Hospital, Paediatric Endocrinology, Hampshire, England and MRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, England
3University Hospital Southampton NHS Foundation Trust, Southampton Children’s Hospital, Paediatric Endocrinology, Hampshire, England and University of Southampton, Faculty of Medicine, Southampton, England

Childhood osteoporosis leads to increased propensity to fracture, and thus is an important cause of morbidity, pain and healthcare utilisation. Osteoporosis in children may be caused by a primary bone defect or secondary to an underlying medical condition and/or its treatment. Primary osteoporosis is rare, but there is an increasing number of children with risk factors for secondary osteoporosis. Therefore it is imperative that all paediatricians are aware of the diagnostic criteria and baseline investigations for childhood osteoporosis to enable timely referral to a specialist in paediatric bone health. This review will discuss the approach to diagnosis, investigation and management of childhood osteoporosis, with particular consideration to advances in molecular diagnosis of primary bone disorders, and current and emerging therapies for fracture reduction.

Keywords: Childhood, management, osteoporosis

David B.N. Lim, Rebecca J. Moon, Justin H. Davies. Advances in Diagnosis and Management of Childhood Osteoporosis. J Clin Res Pediatr Endocrinol. 2022; 14(4): 370-384

Corresponding Author: Justin H. Davies, United Kingdom
Manuscript Language: English
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